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China Manufacturer Anti Cancer Medicine Tretinoin Powder

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Complex Nature Biotechnology CO., LTD.

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China Manufacturer Anti Cancer Medicine Tretinoin Powder

Brand Name : complex

Model Number : BGH-337

Certification : ISO9001/Halal/Kosher

Place of Origin : china

MOQ : 1kg

Price : US$61/kg

Payment Terms : L/C, D/A, D/P, T/T, Western Union, MoneyGram

Supply Ability : 5000000kg per year

Delivery Time : 3 workdays after payment

Packaging Details : 1kg 5kg 25kg two plastic bag inside,aluminum foil bag or drum outside

Type : Herbal Extract

Variety : tretinoin powder

Form : Powder

Part : body

Packaging : Drum

Place of origin : Shaanxi,China(Mainland)

Key word : tretinoin powder

Color : white powder with slight yellow cast

Water soluble : good water soluble

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China Manufacturer Anti Cancer Medicine Tretinoin Powder
Product Details

Product name: Tretinoin
Active ingredient: Tretinoin
CAS NO.: 302-79-4
Molecular formula: C20H28O2
Molecular Weight: 300.44
Characters: white powder with slight yellow cast
Usage: Pharmaceuticals, healthcares,and cosmetics

China Manufacturer Anti Cancer Medicine Tretinoin Powder

Product Description

Successfully treating acute promyelocytic leukemia (APL) with Tretinoin was a major breakthrough in APL therapy. It works in APL because the majority of cases involve a chromosomal translocation of chromosomes 15 and 17, which causes genetic fusion of the retinoic acid receptor (RAR) gene to the promyelocytic leukemia (PML) gene.This fusion PML-RAR protein is responsible for preventing immature myeloid cells from differentiating into more mature cells. This block in differentiation is thought to cause leukemia. ATRA acts on PML-RAR to lift this block, causing the immature promyelocytes to differentiate to normal mature blood cells thus decreasing promyelocytes.

Product Analysis

Item	Specification	Result	Method
BasicProduct Information
Product name	tretinoin powder
Part of the Plant	body	Conform	/
Country of Origin	China	Conform	/
Organoleptic Data
Appearance	Fine powder	Conform	NLS-QCS-1008
Color	white powder with slight yellow cast	Conform	GB/T 5492-2008
Odor& Taste	Characteristic	Conform	GB/T 5492-2008
Process Data
Solvent(s) Used	Water and ethyl alcohol	Conform	/
Extract ration	/	Conform
Content	Paeoniflorin≥98%	98.12
Drying Method	Spray drying	Conform	/
Excipient	Maltodextrin	Conform	/
Physical Characteristics
Particle Size (80 mesh)	98.0%pass 80mesh	Conform	GB/T 5507-2008
Moisture	<5.0%	2.8%	GB/T 14769-1993
Ash Content	<4.0%	1.4%	AOAC 942.05, 18th
Solvent Residue	Eur. Pharm	Conform	NLS-QCS-1007
Heavy Metals
Total Heavy Metals	<10 ppm	Conform	USP <231>, method II
Arsenic	<1.0 ppm	Conform	AOAC 986.15, 18th
Lead	<1.0 ppm	Conform	AOAC 986.15, 18th
Mercury	<0.5 ppm	Conform	AOAC 971.21, 18th
Pesticide Residue
666	<0.2ppm	Conform	GB/T5009.19-1996
DDT	<0.2ppm	Conform	GB/T5009.19-1996
Microbiology
Total Plate Count	<1,000cfu/g	17cfu/g	AOAC 990.12, 18th
Total Yeast & Mold	<100cfu/g	8cfu/g	FDA (BAM) Chapter 18, 8th Ed.
E. Coli	Negative	Negative	AOAC 997.11, 18th
Salmonella	Negative	Negative	FDA (BAM) Chapter 5, 8th Ed.

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